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C V C Prasad Selected Research

2- (2- (3,5- difluorophenyl)- 2- hydroxyacetamido)- N- (3- methyl- 4- oxo- 4,5- dihydro- 3H- benzo(d)(1,2)diazepin- 5- yl)propanamide

7/2007Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): a gamma-secretase inhibitor with Abeta lowering activity in a transgenic mouse model of Alzheimer's disease.

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C V C Prasad Research Topics

Disease

3Alzheimer Disease (Alzheimer's Disease)
12/2007 - 07/2007

Drug/Important Bio-Agent (IBA)

2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
12/2007 - 07/2007
1EnzymesIBA
12/2007
1Pharmaceutical PreparationsIBA
12/2007
1Peptides (Polypeptides)IBA
10/2007
1Amyloid beta-PeptidesIBA
10/2007
1Gamma Secretase Inhibitors and ModulatorsIBA
10/2007
12- (2- (3,5- difluorophenyl)- 2- hydroxyacetamido)- N- (3- methyl- 4- oxo- 4,5- dihydro- 3H- benzo(d)(1,2)diazepin- 5- yl)propanamideIBA
07/2007